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The Collagen Gain Fades Outside Industry Trials

Twenty three trials pooled together looked good for skin. Sorted by who paid for them, the gain vanished in the trials the trade had not funded.

A scoop in the coffee.

Collagen powder now sells by the tonne.

The pitch runs simple. Eat collagen, rebuild skin.

Your gut has other plans…

It cuts the powder into loose amino acids first.

// Quick Check

First reaction?

Last year two researchers pooled 23 trials on skin.

That covered 1,474 people, on collagen or on a dummy.

Stacked together the numbers looked good. Hydration up, stretch up, lines down.

Then they sorted the trials by who paid…

// The Facts

23 trials pooled, covering 1,474 people.
0 benefit left in the trials with no trade money behind them.
0 again, once only the high quality trials counted.

The makers pushed back hard. They say some trials sit under the wrong funder, and that doses and durations were typed up wrong. The journal has run comment letters on it, not a corrected pool, so read this as a strong signpost rather than a closed case.

↗ Source: Myung and Park, American Journal of Medicine, 2025

↗ Source: the trade response, NutraIngredients, 2025

The gain shows up where the maker paid.

So what does hold skin, in trials nobody sells?

In Australia 903 adults were split into two habits. One group creamed daily, the other used it as they liked.

Four and a half years on, the daily group aged 24% less by the skin scores.

In that group the graders found no measurable ageing at all.

// The Fix

Cream, protein, vitamin C

// The Steps

What Holds Skin And Tendon

None of this needs a tub of powder.

01 Cream the face and hands each morning.
02 Hit your protein at every meal, powder or not.
03 Keep vitamin C on the plate, since collagen needs it.
04 For a grumpy tendon, try 15 g of gelatin with vitamin C.
05 Take that an hour before you load the tendon.

↗ Source: Hughes, Annals of Internal Medicine, 2013

↗ Source: Shaw, Am J Clin Nutr, 2017

// Quick Wins

Gelatin is collagen, at a fraction of the price. The sunscreen trial used SPF 15 and graded the back of the hand.

That tendon study read a blood marker, not fewer injuries. Eight men, one lab, three days.

Happy on your powder? Nothing here says stop. It just says the skin case is unproven.

Most collagen copy quotes a trial the seller funded.

I spend more than $20,000 a year on private research… the sort hedge funds pay for. Walled off from the public.

Then I check who paid for it, every time.

My own tub sat in the cupboard for a year. The sunscreen gets used daily, and that is one man’s call.

// Your Pick

Where do you stand on collagen?

Pick one and hit send.

🧺 Taking it daily
 
🤷 Tried it, stopped
 
🚫 Never bothered
 
🧪 Waiting for better proof

Stay primal,
Dex

Primal Code

// Read Next

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